In a dynamic new portrayal of Arthur Conan Doyle's most famous characters, SHERLOCK HOLMES sends Holmes (Downey Jr.) and his stalwart partner, Dr. Watson (Law) on their latest challenge. The only woman ever to have bested Holmes, Irene Adler (McAdams) again sparks her tempestuous relationship with the detective, while a mysterious new nemesis -- Blackwood (Strong) -- constructs a deadly plot that could destroy the country. Revealing fighting skills as lethal as his legendary intellect, Holmes will battle as never before to bring down Blackwood and unravel his plan.